Biased Ligands. Better Drugs.

Oliceridine (TRV130) - Mu Opioid Biased Ligand for Acute Pain

Target Indication Lead
Optimization
Preclinical
Development
Phase
1
Phase
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Phase
3
OwnershipCollaborator
TRV027 Angiotensin II type 1 receptor Acute Heart Failure intravenous Allergan
Oliceridine (TRV130) Mu-receptor Moderate to
Severe Pain
intravenous Trevena Logo
TRV734 Mu-receptor Moderate to
Severe Pain
oral Trevena Logo
TRV250 Delta-receptor Treatment Refractory Migraine oral Trevena Logo

Oliceridine (TRV130) is an intravenous G protein biased ligand that targets the mu opioid receptor. Trevena is developing TRV130 for the treatment of moderate to severe acute pain where intravenous therapy is preferred, with a clinical development focus in acute postoperative pain.

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